Patent 10138487 was granted and assigned to University of Central Lancashire on November, 2018 by the United States Patent and Trademark Office.
Provided are aptamers able to bind to ligands associated with cancer cells. The ligands may particularly be associated with brain cancers, such as gliomas. The aptamers may be used therapeutically for the prevention and/or treatment of such cancers. Aptamers may be associated with anti-cancer agents, or with detection moieties. Also provided as pharmaceutical compositions and methods of treatment employing such aptamers.