A containment booth assembly includes a floor, a plurality of vertical sidewalls, and a plurality of sliding panels corresponding to each of the vertical sidewalls. The plurality of sliding panels define an extendible top portion, the extendible top portion extendible upwardly and configured to interface with a ceiling surface of a room above the containment booth assembly. In a non-limiting aspect or embodiment, one or more of the plurality of vertical sidewalls is rotatably mounted to vertical support beams and define an extendible side portion. The extendible side portion is extendible horizontally and configured to interface with a wall surface of the room beside the containment booth assembly.