A syringe barrel including a tubular, barrel body operable to receive a syringe plunger at a proximal end thereof and a syringe needle at a distal end and sidewalls of said syringe body being flexible and elliptical in cross-section and opposing compression of said syringe barrel at opposite ends a major axis of said syringe barrel cross-section serving to operably flex the elliptical cross-section of said syringe body into a more circular cross-sectional configuration and increasing the volume of said syringe barrel body and concomitantly serving to create a relative vacuum within said syringe body as compared with the configuration of said syringe tubular, barrel body prior to application of said compression.