An aircraft thermal management system includes a first fluid system containing a first fluid, a fluid loop containing a thermally neutral heat transfer fluid, a second fluid system containing a second fluid, a first heat exchanger configured to transfer heat from the first fluid to the thermally neutral heat transfer fluid, and a second heat exchanger configured to transfer heat from the thermally neutral heat transfer fluid to the second fluid. The fluid loop is configured to provide the thermally neutral heat transfer fluid to the first heat exchanger at a pressure that matches the pressure of the first fluid.