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US Patent 10081667 Composition and method for therapeutic agent delivery during pregnancy

Patent 10081667 was granted and assigned to University of Mississippi Medical Center on September, 2018 by the United States Patent and Trademark Office.

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Patent
Patent
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Patent attributes

Patent Applicant
University of Mississippi Medical Center
University of Mississippi Medical Center
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Current Assignee
University of Mississippi Medical Center
University of Mississippi Medical Center
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
100816670
Patent Inventor Names
Gene L. Bidwell, III0
Eric M. George0
Date of Patent
September 25, 2018
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Patent Application Number
149174600
Date Filed
October 1, 2014
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Patent Citations Received
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US Patent 11564991 Molecular-size of elastin-like polypeptide delivery system for therapeutics modulates intrarenal deposition and bioavailability
Patent Primary Examiner
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Karlheinz R. Skowronek
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Patent abstract

A composition including an elastin-like polypeptide (ELP) coupled to a therapeutic agent is provided. The ELP comprises at least about 5 repeats of the amino acid sequence VPGXG. Further provided is a method of using the composition for therapeutic agent delivery during pregnancy to reduce the amount of the therapeutic agent crossing a placenta in a pregnant subject. The method includes administering to the pregnant subject an effective amount of the composition comprising the ELP coupled to the therapeutic agent.

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