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US Patent 10059989 Transposition of native chromatin for personal epigenomics

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Is a
Patent
Patent

Patent attributes

Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
10059989
Date of Patent
August 28, 2018
Patent Application Number
14784250
Date Filed
May 20, 2014
Patent Citations Received
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US Patent 11492612 Methods of determining a surgical margin and methods of use thereof
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US Patent 11505828 Methods for spatial analysis using RNA-templated ligation
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US Patent 12129516 Quantitative and automated permeabilization performance evaluation for spatial transcriptomics
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US Patent 11467153 Methods for processing nucleic acid molecules
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US Patent 11473125 Methods and compositions for nucleic acid analysis
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US Patent 11473138 Methods and systems for processing polynucleotides
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US Patent 12117439 Compositions and methods for using fixed biological samples
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US Patent 12131805 Sequencing methods
0
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Patent Primary Examiner
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Cynthia B Wilder
Patent abstract

Provided herein is a method for analyzing polynucleotides such as genomic DNA. In certain embodiments, the method comprises: (a) treating chromatin isolated from a population of cells with an insertional enzyme complex to produce tagged fragments of genomic DNA; (b) sequencing a portion of the tagged fragments to produce a plurality of sequence reads; and (c) making an epigenetic map of a region of the genome of the cells by mapping information obtained from the sequence reads to the region. A kit for performing the method is also provided.

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