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US Patent 10048275 Cardiotoxicity screening methods

Patent 10048275 was granted and assigned to Q-State Biosciences on August, 2018 by the United States Patent and Trademark Office.

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Patent
Patent

Patent attributes

Patent Applicant
Q-State Biosciences
Q-State Biosciences
Current Assignee
Q-State Biosciences
Q-State Biosciences
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
10048275
Patent Inventor Names
Christopher Werley0
Adam Cohen0
Graham Dempsey0
Joel Kralj0
Date of Patent
August 14, 2018
Patent Application Number
15067610
Date Filed
March 11, 2016
Patent Citations Received
‌
US Patent 12076437 Proangiogenic protein cocktails delivered in custom biomaterials to revascularize ischemic tissue
0
Patent Primary Examiner
‌
Satyendra K Singh
Patent abstract

Screening compounds by exposing a plurality of cardiomyocytes to a compound, wherein the cardiomyocytes express an optogenetic reporter of membrane potential and an optogenetic reporter of calcium level; receiving light from the optogenetic reporter of membrane potential; creating an AP waveform using the received light; and analyzing the AP waveform to determine the presence or absence of a risk for arrhythmia associated with the compound.

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