Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Dmitry Samarsky0
Tod M. Woolf0
William Salomon0
Anastasia Khvorova0
James Cardia0
Joanne Kamens0
Date of Patent
August 7, 2018
0Patent Application Number
130697800
Date Filed
March 23, 2011
0Patent Citations Received
...
Patent Primary Examiner
Patent abstract
The present invention relates to RNAi constructs with minimal double-stranded regions, and their use in gene silencing. RNAi constructs associated with the invention include a double stranded region of 8-14 nucleotides and a variety of chemical modifications, and are highly effective in gene silencing. The RNAi constructs may be, for instance, miRNA constructs that are miRNA modulators.
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