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US Patent 10030012 Piperidin-1-yl and azepin-1-yl carboxylates as muscarinic M4 receptor agonists

Patent 10030012 was granted and assigned to Heptares Therapeutics on July, 2018 by the United States Patent and Trademark Office.

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Is a
Patent
Patent
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Patent attributes

Patent Applicant
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Heptares Therapeutics
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Current Assignee
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Heptares Therapeutics
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
100300120
Patent Inventor Names
David Livermore0
Giles Brown0
Kathryn White0
Michael O'Brien0
Miles Congreve0
Date of Patent
July 24, 2018
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Patent Application Number
154559460
Date Filed
March 10, 2017
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Patent Citations Received
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US Patent 11773090 Pharmaceutical compounds
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US Patent 12024499 Muscarinic agonists
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US Patent 11945801 Bicyclic aza compounds as muscarinic M
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US Patent 11834407 Substituted cyclohexanes as muscarinic M1 receptor and/or M4 receptor agonists
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Patent Primary Examiner
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Brian E McDowell
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Patent abstract

The present invention provides muscarinic M4 receptor agonists of formula (I) and pharmaceutically acceptable salts thereof, wherein m, n, p, q, R, R2 and R3 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases such as schizophrenia, Alzheimer's disease and various cognitive disorders as well as in the treatment or alleviation of pain.

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