Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Hiroyuki Tsunoda0
Tomoyuki Igawa0
Date of Patent
July 3, 2018
Patent Application Number
11910128
Date Filed
March 31, 2006
Patent Citations Received
...
Patent Primary Examiner
Patent abstract
In the course of the present invention, it was discovered that one could regulate association between polypeptides by modifying amino acid residues that form the interface during the association to amino acids carrying the same type of charge. In this context, the present invention enables efficient formation of heterologous molecules. For example, the present invention can be suitably applied to the preparation of bispecific antibodies.
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