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US Patent 10005737 Methods of regioselective synthesis of 2,4-disubstituted pyrimidines

Patent 10005737 was granted and assigned to Vertex Pharmaceuticals on June, 2018 by the United States Patent and Trademark Office.

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Patent abstract

The present invention relates to the novel regioselective syntheses of 2,4-disubstituted pyrimidines through sequential nucleophilic aromatic substitutions.

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