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US Patent 10004782 Glucokinase activator compositions for the treatment of diabetes

Patent 10004782 was granted and assigned to vTv Therapeutics on June, 2018 by the United States Patent and Trademark Office.

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Patent attributes

Patent Applicant

vTv Therapeutics

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Current Assignee

vTv Therapeutics

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Maria Carmen Valcarce Lopez0

Tung Fong0

Date of Patent

June 26, 2018

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Patent Application Number

140719760

Date Filed

November 5, 2013

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Patent Citations Received

US Patent 11833136 Therapeutic uses of glucokinase activators in combination with insulin or insulin analogs

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US Patent 11974989 Therapeutic uses of glucokinase activators in combination with insulin or insulin analogs

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US Patent 11963947 Pharmaceutical combination, composition and compound preparation comprising glucokinase activator and DPP-IV inhibitor, and preparation method and use thereof

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US Patent 10588943 Glucokinase activator compositions for the treatment of diabetes

US Patent 10952993 Therapeutic uses of glucokinase activators in combination with insulin or insulin analogs

US Patent 10980861 Glucokinase activator compositions for the treatment of diabetes

Patent Primary Examiner

Christina Marchetti Bradley

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Patent abstract

The present invention relates to pharmaceutical compositions comprising {2-[3-cyclohexyl-3-(trans-4-propoxy-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid (FRI-1) in combination with an anti-diabetic drug selected from the group consisting of metformin, sitagliptin or exenatide. The present invention also relates to the use of the pharmaceutical compositions in restoring insulin sensitivity and treating type II diabetes, including reducing body weight in subjects undergoing type II diabetes treatment.

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