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US Patent 10000791 Measurement method for human pancreatic lipase activity

Patent 10000791 was granted and assigned to Asahi Kasei Pharma on June, 2018 by the United States Patent and Trademark Office.

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Patent
Patent

Patent attributes

Patent Applicant
Asahi Kasei Pharma
Asahi Kasei Pharma
Current Assignee
Asahi Kasei Pharma
Asahi Kasei Pharma
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
10000791
Date of Patent
June 19, 2018
Patent Application Number
14775919
Date Filed
April 17, 2014
Patent Primary Examiner
‌
Scott Long
Patent abstract

A measurement method for human pancreatic lipase activity in a sample, includes bringing a bile acid that makes a pH for giving a maximum value of human pancreatic lipase activity to be lower than 7.7, a diglyceride and a colipase into contact with the sample at pH 7.4 or lower; and detecting a signal amount varying in accordance with the human pancreatic lipase activity in the sample, and the bile acid is a bile acid containing: one of or two or more of a-type bile acids selected from the group consisting of GDCA, GCDCA, TDCA, TCDCA and salts thereof; and/or a combination of one of or two or more of b-1-type bile acids selected from the group consisting of GCA, GUDCA, TCA, TUDCA and salts thereof, and one of or two or more of b-2-type bile acids selected from the group consisting of DCA, CDCA and salts thereof.

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