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The Effects of Eccentric Cycling Exercise Program in Chronic Kidney Disease Patients

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clinicaltrials.gov/study/NCT06551311
Is a
‌
Clinical study
0

Clinical Study attributes

NCT Number
NCT065513110
Health Conditions in Trial
Chronic kidney disease
Chronic kidney disease
0
Trial Recruitment Size
900
Trial Sponsor
National Cheng Kung University
National Cheng Kung University
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Clinical Trial Start Date
July 1, 2023
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Primary Completion Date
October 30, 2024
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Study Completion Date
December 31, 2025
0
Clinical Trial Study Type
Interventional0
Interventional Trial Purpose
Prevention0
Intervention Type
Behavioral0
Interventional Trial Phase
Not Applicable0
Official Name
To Explore Efficacy and Load of Eccentric Cycling Training in Older CKD Patients With or Without Sarcopenia0
Last Updated
August 13, 2024
0
Allocation Type
Randomized0
Intervention Model
Parallel Assignment0
Masking Type
Single0
Masked Party
Participant0

Other attributes

Intervention Treatment
cycling training exercise0
Study summary

Progress in medical technology, enhancements in environmental cleanliness, and elevated living conditions have notably prolonged the mean life expectancy, resulting in a swift increase in the aging population. The prevalence of Chronic Kidney Disease (CKD) is more pronounced among the elderly in contrast to younger demographics. With the aging of the CKD population, the capacity to autonomously handle daily activities becomes a critical concern. This demographic frequently encounters concurrent health conditions, a decrease in self-care capabilities, general health decline, and diminished quality of life. Recent studies suggest that physical activity has the potential to enhance cardiovascular health, cardiopulmonary endurance, muscle strength, quality of life, uremic toxin management, and inflammation levels among individuals with CKD. Given that CKD patients often exhibit sedentary behavior and reduced exercise capacity, eccentric cycling exercises may be particularly well-suited for this demographic. Compared to concentric contractions, eccentric contractions subject the muscles to higher tension. Since muscle growth partially depends on the "stress exerted on muscle fibers"-meaning the greater the stress, the more stimulation the muscles receive-training focused on eccentric contractions could provide more stimulation and promote greater muscle growth. In recent studies, eccentric cycling has emerged as a feasible and promising aerobic exercise intervention. It can provide a safe and appropriate amount of exercise while relatively reducing joint pressure. This novel combined aerobic and anaerobic exercise method is particularly beneficial for individuals with weaker lower limb muscles, lower joint pressure tolerance, poor metabolic and cardiovascular function, and a tendency to fatigue.

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