Rx Bandz, LLC SBIR Phase I Award, November 2022

Epinephrine and other medications are  sensitive to oxygen.  When the compounds comes in contact with Oxygen, which is unpreventable, the compound starts to degrade.  SMS is commonly used as a preservative to reduce oxygenation. However, it is impossible to prevent the leak of oxygen into the epinephrine within an auto-injector or prefilled syringe.  Even small amounts of oxygen over time cause degradation of the epinephrine.  Rx Bandz proposes adding SMS, a oxygen- reducing agent in the hydraulic fluid.  This will allow manufacturers to  to reduce the amount of  sms in the commonly used 1 mg in cartridge extends from 4-5 months in the customer’s hands (after manufacture, storage and shipping) to 18 months.