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Postoperative Knee Strength Following Total Knee Replacement: A Double-Blinded Randomized Comparison Study

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Contents

clinicaltrials.gov/study/NCT01620047
Is a
‌
Clinical study
0

Clinical Study attributes

NCT Number
NCT016200470
Trial Recruitment Size
600
Trial Sponsor
University of South Florida
University of South Florida
0
Trial Collaborator
Tampa General Hospital
Tampa General Hospital
0
Clinical Trial Start Date
2011
0
Primary Completion Date
2012
0
Study Completion Date
2012
0
Clinical Trial Study Type
Interventional0
Interventional Trial Purpose
Treatment0
Intervention Type
Drug0
Interventional Trial Phase
Not Applicable0
Participating Facility
Tampa General Hospital
Tampa General Hospital
0
Official Name
Postoperative Knee Strength Following Total Knee Replacement: A Double-Blinded Randomized Comparison Study0
Last Updated
November 11, 2013
0
Allocation Type
Randomized0
Intervention Model
Parallel Assignment0
Masking Type
Quadruple0
Masked Party
Care Provider0
Outcomes Assessor0
Participant0
Investigator0

Other attributes

Intervention Treatment
Ropivacaine0
Fentanyl0
Study summary

Major surgery involving the knee is often associated with severe postoperative pain. Postoperative pain control remains a significant contributor to delayed recovery and length of hospital stay. Approaches to minimize postoperative pain after surgery are a matter of major concern due to the need for early mobilization, a crucial factor in good postoperative rehabilitation. Femoral nerve blocks by either continuous infusion or single injection of anesthetics provide an effective method for analgesia while minimizing the need for systemic opioid therapy, reducing the opioid induced side effects, and facilitating early ambulation. Administration of fentanyl has shown to be a highly effective method to control pain after Total Knee Replacement (TKR). The investigators hypothesize that fentanyl infusions will result in greater post-operative strength in the operative knee.

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