Is a
Clinical Study attributes
NCT Number
Health Conditions in Trial
Trial Recruitment Size
5130
Trial Sponsor
Trial Collaborator
Clinical Trial Start Date
2014
0Primary Completion Date
2017
0Study Completion Date
2017
0Clinical Trial Study Type
Interventional0
Interventional Trial Purpose
Prevention0
Intervention Type
Other0
Intervention Name
Usual Care0
Enhanced oropharyngeal suction0
Interventional Trial Phase
Not Applicable0
Participating Facility
Official Name
Oral Suction Intervention to Reduce Aspiration and Ventilator Events: NO-ASPIRATE0
Last Updated
August 15, 2019
0Allocation Type
Randomized0
Intervention Model
Parallel Assignment0
Masking Type
Triple0
Masked Party
Care Provider0
Participant0
Outcomes Assessor0
Study summary
Insertion of a breathing tube to enable treatment with mechanical ventilation (respirator) is often associated with complications, such as infection and lung injury. Leakage of secretions around the breathing tube (microaspiration) is a major factor leading to complications. The investigators propose that a standardized, enhanced oral suction protocol will be effective in reducing microaspiration and harms associated with mechanical ventilation. The investigators hypothesize that those randomized to the enhanced oral suction protocol will have less microaspiration and other ventilator-associated conditions than those in the usual care, standard suction group.
Timeline
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