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FT536 Monotherapy and in Combination With Monoclonal Antibodies in Advanced Solid Tumors

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Contents

clinicaltrials.gov/study/NCT05395052
Is a
‌
Clinical study
0

Clinical Study attributes

NCT Number
NCT053950520
Health Conditions in Trial
Ovarian cancer
Ovarian cancer
0
Head and neck cancer
Head and neck cancer
0
‌
Breast Cancer
0
Colorectal cancer
Colorectal cancer
0
Pancreatic cancer
Pancreatic cancer
0
Trial Recruitment Size
50
Trial Sponsor
Fate Therapeutics
Fate Therapeutics
0
Clinical Trial Start Date
May 31, 2022
0
Primary Completion Date
August 11, 2023
0
Study Completion Date
August 11, 2023
0
Clinical Trial Study Type
Interventional0
Interventional Trial Purpose
Treatment0
Intervention Type
Combination Product0
Drug0
Intervention Name
Fludarabine0
FT5360
Cyclophosphamide0
Cetuximab0
Avelumab0
Atezolizumab0
Amivantamab0
Nivolumab0
...
Interventional Trial Phase
Phase 10
Participating Facility
‌
Carolina Biooncology Institute
0
Official Name
A Phase I, Open-Label, Multicenter Study of FT536 as Monotherapy and in Combination With Monoclonal Antibodies in Subjects With Advanced Solid Tumors0
Last Updated
September 21, 2023
0
Allocation Type
Non-Randomized0
Intervention Model
Sequential Assignment0
Masking Type
None (Open Label)0
Study summary

This is a Phase 1 dose-finding study of FT536 given in combination with a monoclonal antibody following lymphodepletion in participants with advanced solid tumors. The study will consist of a dose-escalation stage and an expansion stage where participants will be enrolled into indication-specific cohorts.

Timeline

No Timeline data yet.

Further Resources

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