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Deep Genomics

Deep Genomics

A genetic medicine company that build data platforms using synthetic biology, artificial intelligence and genetic medicine for the development of medical therapies.

OverviewStructured DataIssuesContributors

Contents

Project Saturn Funding Seed Series A Partnerships Wave Life Sciences Patents TimelineTable: Funding RoundsTable: ProductsTable: AcquisitionsTable: SBIR/STTR AwardsTable: PatentsTable: Further ResourcesReferences
deepgenomics.com
Is a
Organization
Organization
Company
Company

Company attributes

Industry
Genomics
Genomics
Genetic engineering
Genetic engineering
Healthcare
Healthcare
Consumer biotechnology
Consumer biotechnology
Biotechnology
Biotechnology
Drug discovery
Drug discovery
Biomedical engineering
Biomedical engineering
Engineering
Engineering
...
Location
Toronto, Prince Edward Island
Toronto, Prince Edward Island
Cambridge, Massachusetts
Cambridge, Massachusetts
Toronto
Toronto
12
Canada
Canada
Ontario
Ontario
12
B2X
B2B
B2B
CEO
Brendan Frey
Brendan Frey
Founder
Brendan Frey
Brendan Frey
Andrew Delong
Andrew Delong
AngelList URL
angel.co/deep-genomics
Pitchbook URL
pitchbook.com/profiles...131283-37
Legal Name
Deep Genomics Inc.
Legal classification
Corporation
Corporation
Date Incorporated
2014
Number of Employees (Ranges)
51 – 20014
Email Address
contact@deepgenomics.com13
press@deepgenomics.com13
bd@deepgenomics.com13
Phone Number
+1647598887913
Full Address
MaRS Centre, 661 University Ave, Suite 480 Toronto, Ontario, Canada, M5G 1M113
Suite 2B, 101 Rogers St, Cambridge, MA MA 0214213
Investors
NJF Capital
NJF Capital
Alexandria Venture Investments
Alexandria Venture Investments
11
CPP Investments
CPP Investments
11
SoftBank Vision Fund
SoftBank Vision Fund
11
UTEST - University of Toronto Early Stage Technology
UTEST - University of Toronto Early Stage Technology
Fidelity Investments
Fidelity Investments
11.2 Capital
11.2 Capital
Bloomberg Beta
Bloomberg Beta
...
Founded Date
2014
14
Total Funding Amount (USD)
236,700,000
Latest Funding Round Date
July 28, 2021
Competitors
BenchSci
BenchSci
Board of Directors
Brendan Frey
Brendan Frey
7
Alex Morgan
Alex Morgan
7
Maryanna Saenko
Maryanna Saenko
7
Tom Hughes
Tom Hughes
7
Dion Madsen
Dion Madsen
7
Matt Cahill
Matt Cahill
7
Adam D'Augelli
Adam D'Augelli
7
CFO
Matt Cahill
Matt Cahill
Key People
Matt Cahill
Matt Cahill
Brendan Frey
Brendan Frey
Latest Funding Type
Series C
Series C
Patents Assigned (Count)
4
Wellfound ID
deep-genomics
Country
Canada
Canada
12
Headquarters
Toronto, Ontario, Canada
Toronto, Ontario, Canada
13

Other attributes

Blog
deepgenomics.com/blog/
Company Operating Status
Active
Contact Page URL
deepgenomics.com/contact/
Latest Funding Round Amount (USD)
180,000,000

Deep Genomics is a medical company focused on developing genetic therapies. It builds artificial intelligence-driven platforms that guide the creation of new medical therapies by blending synthetic biology, artificial intelligence and genetic medicine.

Brendan Frey, Andrew Delong, Hannes Bretschneider and Hui Yuan Xiong founded Deep Genomics in 2015 in Toronto, Ontario, Canada. It has a growing team of geneticists, molecular biologists and chemists from University of Cambridge, Massachusetts Institute of Technology (MIT), Stanford University, University of Toronto, University of California, San Diego, University of Washington and University of Waterloo. It is funded by primarily by Bay Area investors and aims to develop new ways of detecting and treating disease using biologically accurate artificial intelligence technology.

Deep Genomics uses neural networks to analyze genomic data, allowing scientists to identify the genes that cause diseases and develop drugs that deal with them. It has also specialized in finding elusive and less direct disease triggers in a person’s genome. Deep learning can identify patterns in DNA that might contribute to diseases such as spinal muscular atrophy and nonpolyposis colorectal cancer

CEO of Deep Genomics Brendan Frey — Deep Genomics: Changing the Course of Genomic Medicine

Project Saturn

Project Saturn is the name of Deep Genomics artificially intelligent drug prediction and design platform. The project is analyzing over 69 billion oligonucleotides against 1 million gene targets and narrowing down their results to produce 1000 potential new compounds that will work to have the predicted biological affect. The platform is able to continuously improve its predictions in a closed loop based on its failures and successes in reference to human cells. The system is designed to predict what affect an antisense oligonucleotide compound (AGO) on human cells, taking into account individual genotype and multiple biological mechanisms.

Funding
Seed

On November 18th, 2015 raised $3,700,000 in seed funding from True Ventures, Bloomberg Beta, and 11.2 Capital.

Series A

After completing its series A funding round on September 25th, 2017, Deep Genomics raised $13,000,000 in funding from Khosla Ventures and True Ventures.

Partnerships
Wave Life Sciences

Deep Genomics announced that it will begin working with Wave Life Sciences on April 10th, 2018. Deep Genomics will be offering Wave Life Sciences access to their machine learning platforms to help increase the efficiency of developing new therapies for treating genetic neuromuscular disorders. The two companies will be collaborating to identify therapeutic oligonucleotides that act on gene targets which reduce the negative effects of genes causing neuromuscular disease on April 10th, 2018. Deep Genomics will be offering Wave Life Sciences access to their machine learning platforms to help increase the efficiency of developing new therapies for treating genetic neuromuscular disorders. The two companies will be collaborating to identify therapeutic oligonucleotides that act on gene targets which reduce the negative effects of genes causing neuromuscular disease.

Patents

Patent description
Inventor
Status
Date
App/pub number

Methods and systems for producing an expanded training set for machine learning using biological sequences

Brendan John Frey, Andrew Thomas Delong, Hui Yuan Xiong

Application

2017-11-09

WO2017190211A1

Neural network architectures for linking biological sequence variants based on molecular phenotype, and systems and methods therefor

Brendan Frey, Andrew Delong

Application

2016-12-22

WO2016201564A1

Neural network architectures for scoring and visualizing biological sequence variations using molecular phenotype, and systems and methods therefor

Andrew Delong, Brendan Frey

Application

2017-11-16

WO2017193198A1

System and method for training neural networks

Hui Yuan Xiong, Andrew Delong, Brendan Frey

Application

2017-01-26

US20170024642A1

Systems and methods for classifying, proiritizing and interpreting genetic variants and therapies using a deep neural network

Brendan Frey, Michael K.K. Leung, Andrew Thomas Delong, Hui Yuan Xiong, Babak Alipanahi, Leo J. Lee, Hannes Bretschneider

Application

2016-12-15

CA2894317A1

Timeline

No Timeline data yet.

Funding Rounds

Products

Acquisitions

SBIR/STTR Awards

Patents

Further Resources

Title
Author
Link
Type
Date

A sanctuary for startups: How an aging church became home to some of U of T's newest ventures

University of Toronto​

https://www.utoronto.ca/news/sanctuary-startups-how-aging-church-became-home-some-u-t-s-newest-ventures

AI startup Deep Genomics lands financing as it aims to ‘flip medicine on its back’

Sean Silcoff

https://www.theglobeandmail.com/report-on-business/toronto-ai-startup-deep-genomics-lands-financing/article36383250/

Brendan Frey - Genome Reprogramming

https://www.youtube.com/watch?v=tIVNjCpqCaY

December 9, 2017

Brendan Frey — Deep Genomics: Changing the Course of Genomic Medicine

https://www.youtube.com/watch?v=i_nGJ8p3rk0

July 1, 2017

Correction of a splicing defect in a mouse model of congenital muscular dystrophy type 1A using a homology-directed-repair-independent mechanism. - PubMed - NCBI

Kemaladewi Du, Maino E, Hyatt E, Hou H, Ding M, Place KM, Zhu X, Bassi P, Baghestani Z, Deshwar AG, Merico D, Xiong HY, Frey BJ, Wilson MD, Ivakine EA, Cohn RD

https://www.ncbi.nlm.nih.gov/pubmed/28714989

Academic paper

References

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