SBIR/STTR Award attributes
In order to meet DHA’s need for quantitative imaging of the olfactory neuroepithelium (ON) ChromoLogic proposes to develop a Neuroepithelial Optical Coherence Tomography (NOCT) system that uses an optical coherence tomography (OCT) endoscope to generate 3D images of the ON. The device is non-invasive and can be used to determine the cellular and functional characteristics of olfactory neuroepithelium with limited anesthesia. The device can determine thickness of the mucus layer, epithelium, and the lamina propria and characterize important properties of the cellular layers. This is made possible by a custom-designed OCT probe that can be inserted into the nose for high resolution imaging and analysis software that can quantify the thickness of the various layers from the resulting 3D images.
