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CRP and Thoracic Emergency Ultrasound in Pneumonia

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clinicaltrials.gov/study/NCT03212248
Is a
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Clinical study
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Clinical Study attributes

NCT Number
NCT032122480
Health Conditions in Trial
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Community-acquired pneumonia
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Ultrasound
Ultrasound
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Trial Recruitment Size
700
Clinical Trial Start Date
January 2, 2016
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Primary Completion Date
April 30, 2016
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Study Completion Date
June 30, 2017
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Clinical Trial Study Type
Observational0
Observational Clinical Trial Type
Case-Only0
Observational Study Perspective
Prospective0
Official Name
CRP (C-Reactive-Protein) and Pneumonia Biomarkers Stratification for Selectively Addressing Priorities in Thoracic Emergency Ultrasound in Pneumonia0
Last Updated
July 11, 2017
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Study summary

This preliminary study investigates in patients with possible clinical diagnosis of pneumonia, clues and biomarker assessed at Emergency Department (ED) triage, potentially predicting detection of lung consolidation by Thoracic-ultrasound (TUS) and/or by Chest-X-Rays. Cough and high admission CRP levels will be defined according to the cutoff defined by ROC analysis, will be challenged if independently associated with TUS lung consolidation detection High level of the chosen biomarker, and any of the considered symptoms, in otherwise not extremely critical patients (CURB65≤3), should prompt to immediate confirm by TUS, during the physical examination. This may limit the need of further radiological investigations allowing targeted workup.

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