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- CRISPR/Cas ToolsClustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR associated (Cas) proteins perform adaptive immune functions in prokaryotic organisms defending against foreign nucleic acids such as viruses. CRISPR/Cas tools have been adapted for use in genome editing and other DNA and RNA targeting applications.
- Cluster: BiotechnologyA cluster of topics related to biotechnology.
- Cluster: Synthetic biologyA cluster of topics related to synthetic biology.
- CRISPR-Cas13A nucleic acid editing technology that targets RNA, analogous to the CRISPR-Cas9 system
- CRISPR-Cas13aThe CRISPR-Cas13a, like other CRISPR-Cas systems functions in bacterial immunity but this system targets invading RNA rather than DNA. CRISPR-Cas13a is being engineered for RNA sensing applications such as live cell RNA tracking and detection of pathogenic viruses or bacteria.
- CRISPR-Cas13bNucleic acid editing technology that targets RNA and is being developed as a tool for editing pathogenic mutations in RNA transcripts.
- CRISPR-Cas13dCRISPR-Cas13d is a type VI CRISPR-Cas system with the RNA-guided RNase effector Cas13d. CRISPR-Cas13d has potential applications in RNA detection, manipulation and therapeutics. The small size of Cas13d is an advantage for packaging and delivery into cells.