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ADHD Remote Technology Study of Cardiometabolic Risk Factors and Medication Adherence

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clinicaltrials.gov/study/NCT05301673
Is a
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Clinical study
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Clinical Study attributes

NCT Number
NCT053016730
Health Conditions in Trial
Attention deficit hyperactivity disorder
Attention deficit hyperactivity disorder
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Trial Recruitment Size
6000
Trial Sponsor
King's College London
King's College London
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Trial Collaborator
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Avon and Wiltshire Mental Health Partnership NHS Trust
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South West London and St George's Mental Health NHS Trust
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East London NHS Foundation Trust
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Barnet, Enfield and Haringey Mental Health NHS Trust
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South London and Maudsley NHS Foundation Trust
South London and Maudsley NHS Foundation Trust
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Clinical Trial Start Date
July 12, 2022
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Primary Completion Date
2025
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Study Completion Date
2025
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Clinical Trial Study Type
Observational0
Observational Clinical Trial Type
Cohort0
Observational Study Perspective
Prospective0
Participating Facility
King's College London
King's College London
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Official Name
ADHD Remote Technology Study of Cardiometabolic Risk Factors and Medication Adherence ('ART-CARMA')0
Last Updated
October 4, 2023
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Study summary

Attention-deficit/hyperactivity disorder (ADHD) is a common psychiatric disorder, with a prevalence among adults of 2.5%. The disorder is diagnosed based on impairing levels of inattentive, hyperactive and impulsive behaviours. Most adults with ADHD present with additional mental health problems. Adults with ADHD have an increased risk to develop so-called cardiometabolic illnesses, such as type-2 diabetes, obesity and cardiovascular disease (e.g., heart failure). However, detailed knowledge about the screening, diagnosis and management of adults with ADHD and co-occurring cardiometabolic illnesses is lacking. The purpose of ART-CARMA is to (1) obtain real-world data from adults with ADHD daily life on the extent to which ADHD medication treatment and physical activity, individually and jointly, may influence cardiometabolic risks in adults with ADHD, and (2) obtain real-world data of patterns of taking ADHD medication and reasons for not taking medication, over a remote monitoring period of 12 months. ART-CARMA benefits from the ADHD Remote Technology ('ART') assessment and monitoring system for adults with ADHD (developed by Kuntsi, Dobson, et al.), and the RADAR-base mobile-health platform to which it is linked (developed by Dobson et al; http://www.radar-base.org). ART consists of both active (e.g., questionnaires) and passive (smartphone and a wearable device) monitoring. ART-CARMA will use remote measurement technology (RMT) in adults with ADHD to carry out unobtrusive, real-time data collection over a continuous period of 12 months. By recruiting 300 adults from adult ADHD clinic waiting lists (and a partner/family member/close friend for each of them) and monitoring them remotely, we will obtain objectively measured data relevant to cardiometabolic risk profiles from their daily lives. By targeting the period before starting any ADHD medication through to starting treatment and the subsequent period, up to 12 months in total, we obtain real-time data on multiple parameters, including side effects, that can inform the personalisation of treatment.

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