Clinical Studies Sponsored by Inovio Pharmaceuticals | 27 results

VGX-3100 Delivered Intramuscularly (IM) Followed by Electroporation (EP) for the Treatment of HPV-16 and/or HPV-18 Related Anal or Anal/Peri-Anal, High Grade Squamous Intraepithelial Lesion (HSIL) in Individuals Seronegative for Human Immunodeficiency Virus (HIV)-1/2

Name	NCT Number	Health Conditions in Trial	Clinical Trial Start Date	Study Completion Date	Clinical Trial Study Type
‌ Study of PENNVAX™-B (Gag, Pol, Env) + Electroporation in HIV-1 Infected Adult Participants	NCT01082692		2011	2012	Interventional
‌ Safety, Tolerability and Immunogenicity of INO-4800 for COVID-19 in Healthy Volunteers	NCT04336410		April 3, 2020	July 1, 2021	Interventional
‌ REVEAL 2 Trial (Evaluation of VGX-3100 and Electroporation for the Treatment of Cervical HSIL)	NCT03721978		April 9, 2019	September 14, 2022	Interventional
‌ Medpulser Electroporation With Bleomycin Study to Treat Posterior Head and Neck Squamous Cell Carcinoma	NCT00198328		2004	2007	Interventional
‌ Medpulser Electroporation With Bleomycin Study to Treat Anterior Head and Neck Squamous Cell Carcinoma	NCT00198315	Head and neck cancer	2004	June 1, 2007	Interventional
‌ Trial to Evaluate Safety and Immunogenicity of INO-5150 Alone or With INO-9012 in Men With Prostate Cancer	NCT02514213	Prostate cancer	2015	December 12, 2017	Interventional
‌ Study of VGX-3400X, H5N1 Avian Influenza Virus DNA Plasmid + Electroporation in Healthy Adults	NCT01142362	‌ Healthy	2010	2011	Interventional
‌ A Follow-On Study With an H5 Influenza Vaccine for Subjects Who Participated in Study FLU-001	NCT01403155	‌ Healthy	2011	2012	Interventional
‌ Study Using the Medpulser Electroporation System With Bleomycin to Treat Head and Neck Cancer	NCT00198263	Head and neck cancer	2004	2008	Interventional
‌ Phase I Study of INO-1800 With or Without INO-9112 + EP in Chronic Hepatitis B Subjects	NCT02431312	Hepatitis B	January 12, 2015	May 22, 2018	Interventional
‌ Evaluation of VGX-3100 and Electroporation Alone or in Combination With Imiquimod for the Treatment of HPV-16 and/or HPV-18 Related Vulvar HSIL (Also Referred as: VIN 2 or VIN 3)	NCT03180684		August 31, 2017	December 18, 2020	Interventional
‌ Phase I of Human Papillomavirus (HPV) DNA Plasmid (VGX-3100) + Electroporation for CIN 2 or 3	NCT00685412		2008	2011	Interventional
‌ Immunotherapy in Subjects With HPV-6 Associated Aerodigestive Precancerous Lesions and Malignancies	NCT02241369		2014	2018	Interventional
‌ Safety, Tolerability and Immunogenicity of INO-4800 for COVID19 in Healthy Volunteers	NCT05430958		2022	2024	Interventional
‌ hTERT Immunotherapy Alone or in Combination With IL-12 DNA Followed by Electroporation in Adults With Solid Tumors at High Risk of Relapse	NCT02960594	Lung cancer Colorectal cancer Hepatocellular carcinoma Esophageal cancer Pancreatic cancer Ovarian cancer Head and neck cancer ‌ Breast Cancer	2014	November 9, 2018	Interventional
‌ Open-Label Study of INO-4212 With or Without INO-9012, Administered IM or ID Followed by Electroporation in Healthy Volunteers	NCT02464670	Ebola vaccine	2015	May 24, 2018	Interventional
‌ Dose-ranging Study: Safety, Tolerability and Immunogenicity of INO-4500 in Healthy Volunteers in Ghana	NCT04093076	Lassa fever	January 27, 2021	October 14, 2022	Interventional
‌ Study Using the MedPulser Electroporation System With Bleomycin to Treat Cutaneous and Subcutaneous Cancer	NCT00198276	Cancer	2004	2008	Interventional
‌ Study of HPV Specific Immunotherapy in Participants With HPV Associated Head and Neck Squamous Cell Carcinoma	NCT02163057		August 13, 2014	January 23, 2017	Interventional
‌ A Study of INO-3112 DNA Vaccine With Electroporation in Participants With Cervical Cancer	NCT02172911	Cervical cancer	June 6, 2014	September 7, 2017	Interventional
‌ Safety, Tolerability and Immunogenicity of INO-4500 in Healthy Volunteers	NCT03805984	Lassa fever	May 9, 2019	October 21, 2020	Interventional
‌ INO-5401 + INO-9012 in Combination With Atezolizumab in Locally Advanced Unresectable or Metastatic/Recurrent Urothelial Carcinoma	NCT03502785		May 24, 2018	December 31, 2023	Interventional
‌ INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-Diagnosed Glioblastoma (GBM)	NCT03491683	Glioblastoma	May 31, 2018	December 31, 2023	Interventional
‌ Safety, Tolerability and Immunogenicity of INO-4700 for MERS-CoV in Healthy Volunteers	NCT04588428		June 21, 2021	January 19, 2023	Interventional
‌ VGX-3100 Delivered Intramuscularly (IM) Followed by Electroporation (EP) for the Treatment of HPV-16 and/or HPV-18 Related Anal or Anal/Peri-Anal, High Grade Squamous Intraepithelial Lesion (HSIL) in Individuals Seronegative for Human Immunodeficiency Virus (HIV)-1/2	NCT03499795		May 15, 2018	May 26, 2021	Interventional