US Patent 9944919 Tethering cysteine residues using cyclic disulfides
Patent 9944919 was granted and assigned to Brandeis University on April, 2018 by the United States Patent and Trademark Office.
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Patent abstract
Described herein are compounds and methods for tethering proteins. For example, dimers of proteins, including SOD1 and DJ-1, are described, where the dimers are formed by the covalent bonding of a cysteine on the first monomer to a cysteine on the second monomer via a cyclic disulfide linker. The covalently attached dimers exhibit increased stabilization.
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Patent Inventor Names
Jeffrey N. Agar0
Joseph Salisbury0
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US Patent 09944919 Tethering cysteine residues using cyclic disulfides US Patent 9944919 Tethering cysteine residues using cyclic disulfides
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Patent Number
099449190
Patent Number
99449190
Edits on 25 Sep, 2022
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Is a
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
099449190
Date of Patent
April 17, 2018
0Patent Application Number
152198070
Date Filed
July 26, 2016
0Patent Primary Examiner
Edits on 19 Jan, 2022
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US Patent 09944919 Tethering cysteine residues using cyclic disulfides
Infobox
Is a
Patent applicant
Current assignee
Patent jurisdiction
Patent number
09944919
Date of patent
April 17, 2018
Patent application number
15219807
Date Filed
July 26, 2016
Patent primary examiner
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