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US Patent 8999999 Use of inhibitors of Bruton's tyrosine kinase (Btk)

Patent 8999999 was granted and assigned to Pharmacyclics on April, 2015 by the United States Patent and Trademark Office.

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Contents

Is a
Patent
Patent

Patent attributes

Patent Applicant
Pharmacyclics
Pharmacyclics
Current Assignee
Pharmacyclics
Pharmacyclics
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
8999999
Date of Patent
April 7, 2015
Patent Application Number
13747322
Date Filed
January 22, 2013
Patent Citations Received
‌
US Patent 11944647 Articles of manufacture and methods for treatment using adoptive cell therapy
0
Patent Primary Examiner
‌
Uma Ramachandran
Patent abstract

Disclosed herein are methods for treating a cancer comprising: a. administering a Btk inhibitor to a subject sufficient to result in an increase or appearance in the blood of a subpopulation of lymphocytes defined by immunophenotyping; b. determining the expression profile of one or more biomarkers from one or more subpopulation of lymphocytes; and c. administering a second agent based on the determined expression profile.

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