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US Patent 8697065 Non-natural ribonuclease conjugates as cytotoxic agents

Patent 8697065 was granted and assigned to Quintessence Biosciences on April, 2014 by the United States Patent and Trademark Office.

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Patent abstractTimelineTable: Further ResourcesReferences
Is a
Patent
Patent
1

Patent attributes

Patent Applicant
Quintessence Biosciences
Quintessence Biosciences
1
Current Assignee
Quintessence Biosciences
Quintessence Biosciences
1
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
1
Patent Number
86970651
Patent Inventor Names
Laura E. Strong1
Peter A. Leland1
Thomas Burke1
Date of Patent
April 15, 2014
1
Patent Application Number
139230081
Date Filed
June 20, 2013
1
Patent Citations Received
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US Patent 12129288 Polynucleotides heterodimers of soluble interferon receptors and uses thereof
2
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US Patent 12077790 Optimized binuclease fusions and methods
3
Patent Primary Examiner
‌
Iqbal H Chowdhury
1
Patent abstract

The present invention is directed toward the delivery of a toxic protein to pathogenic cells, particularly cancer cells. In preferred embodiments, the toxic protein is a ribonuclease that has been modified to make it toxic to target cells and that can be conjugated to a target cell-specific delivery vector, such as an antibody, for delivery to pathogenic cells.

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