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US Patent 8637478 Compounds and methods for modulating protein expression

Patent 8637478 was granted and assigned to Ionis Pharmaceuticals on January, 2014 by the United States Patent and Trademark Office.

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Patent abstractTimelineTable: Further ResourcesReferences
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Patent
Patent

Patent attributes

Current Assignee
Ionis Pharmaceuticals
Ionis Pharmaceuticals
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
8637478
Date of Patent
January 28, 2014
Patent Application Number
12742652
Date Filed
November 13, 2008
Patent Citations Received
‌
US Patent 11873490 Antisense oligomers for treatment of conditions and diseases
3
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US Patent 11879125 GalNAc compositions for improving siRNA bioavailability
4
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US Patent 11891605 Reducing intron retention
5
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US Patent 12060558 Methods and compositions for treatment of cholesteryl ester storage disease
6
Patent Primary Examiner
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Kimberly Chong
Patent abstract

The present invention provides compounds and methods for modulating expression of a protein, including, but not limited to, modulating splicing of a pre-mRNA to modulate the amount of one or more variants of a protein.

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