Systems and methods of detecting fatigue and drowsy conditions of vehicle drivers without initially using any disruptive visual and sound alarms, and instead immediately interacting with the driver as to their condition and providing information on rest stops through onboard GPS (global positioning satellite) systems, as well as alerting acquaintances and friends of the driver through telephones such as a cellular phone. The systems and methods can interact with the driver through touch type screens, and/or audible feedback to alert the driver of their condition and to temporarily take the driver off the roads.