US Patent 7745129 Methods for sequencing of a necleic acid

Improved labeled molecule probes for use in biomedical applications including the sequencing of nucleic acid molecules and methods and apparatuses for their use are detailed. Labeled-probe-assemblies, comprising a probe element, for binding to a target molecule, attached to a label-assembly further comprising a linear series of information encoded structures and means for spatially separating these structures, are presented together with methods for extending the label assemblies such that the information encoded structures can be individually resolved, substantially simultaneously, by a readout device.