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Patent attributes
Current Assignee
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Patent Jurisdiction
Patent Number
Date of Patent
February 16, 2010
Patent Application Number
12021578
Date Filed
January 29, 2008
Patent Primary Examiner
Patent abstract
The invention refers to the use of specific cyclolignans, wherein the carbon atoms in positions 9 and 9′ have cis configuration, for inhibition of the insulin-like growth factor-1 receptor. Said compounds can be used for treatment of IGF-1R dependent diseases, such as cancer, psoriasis, atherosclerosis and acromegaly. A preferred compound is picropodophyllin.
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