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US Patent 7659442 Method for making homozygous genetic modifications

Patent 7659442 was granted and assigned to Regeneron Pharmaceuticals, Inc. on February, 2010 by the United States Patent and Trademark Office.

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US Patent 12127537 Genetically modified non-human animals and methods of use thereof
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US Patent 12127536 Humanized M-CSF mice
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US Patent 12089576 Nucleic acids comprising a modified rodent activin a receptor type 1 (Acvr1) gene
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US Patent 12010979 Non-human animals comprising a humanized TTR locus and methods of use
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US Patent 11963521 Humanized IL-4 and IL-4Rα animals
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US Patent 11910787 Rodents having a humanized TMPRSS gene
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US Patent 11889821 Enhanced immunoglobulin diversity
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US Patent 11891618 Mouse comprising a humanized TTR locus with a beta-slip mutation and methods of use
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US Patent 11866794 Cas-ready mouse embryonic stem cells and mice and uses thereof
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Patent abstract

Methods of generating modified embryos and mammals by introduction of donor cells into an early stage embryo are provided, such that the resulting embryo and animal generated therefrom has a significant contribution to all tissues from the donor cells and is capable of transmitting the donor cell DNA.

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US Patent 11778995 Genetically modified non-human animals and methods of use thereof
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US Patent 11766032 Genetically modified non-human animals expressing human EPO
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Patent Inventor Names
David Frendewey0
David M. Valenzuela0
Thomas M. DeChiara0
William Poueymirou0
Wojtek Auerbach0
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US Patent 11696572 Non-human animals comprising a humanized ASGR1 locus
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US Patent 11690362 Nuclease-mediated repeat expansion
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Official Website
https://pdfpiw.uspto.gov/.piw?Docid=07659442
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US Patent 07659442 Method for making homozygous genetic modifications US Patent 7659442 Method for making homozygous genetic modifications

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Patent Number
07659442
Patent Number
7659442

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