Patent 7655762 was granted and assigned to Lexicon Pharmaceuticals, Inc. on February, 2010 by the United States Patent and Trademark Office.
Monoclonal antibodies that specifically bind to ANGPTL4 are provided. Monoclonal antibodies that neutralize at least one activity of ANGPTL4 are provided. Methods of treating a disorder of lipid metabolism using neutralizing monoclonal antibodies are provided.