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US Patent 7414118 Modified oligonucleotides and applications thereof

Patent 7414118 was granted and assigned to Applied Biosystems on August, 2008 by the United States Patent and Trademark Office.

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Patent
Patent

Patent attributes

Current Assignee
Applied Biosystems
Applied Biosystems
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
7414118
Date of Patent
August 19, 2008
Patent Application Number
11372984
Date Filed
March 9, 2006
Patent Citations Received
‌
US Patent 12110552 Methods for simultaneous amplification of target loci
3
‌
US Patent 12024738 Methods for cancer detection and monitoring
4
‌
US Patent 12065703 System and method for cleaning noisy genetic data and determining chromosome copy number
5
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US Patent 12084720 Assessing graft suitability for transplantation
6
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US Patent 11746376 Methods for amplification of cell-free DNA using ligated adaptors and universal and inner target-specific primers for multiplexed nested PCR
‌
US Patent 11939634 Methods for simultaneous amplification of target loci
7
‌
US Patent 11946101 Methods and compositions for determining ploidy
8
‌
US Patent 12020778 Methods for non-invasive prenatal ploidy calling
9
Patent Primary Examiner
‌
Jezia Riley
Patent abstract

Disclosed, among other things, are primers containing certain modified nucleobases in the 3′ terminal region of the primers that provide reduced formation of primer-dimers during amplification reactions, and various methods of use thereof.

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