US Patent 7402570 Amplification of human MDM2 gene in human tumors
Patent 7402570 was granted and assigned to Johns Hopkins University on July, 2008 by the United States Patent and Trademark Office.
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Patent Inventor Names
Bert Vogelstein0
Kenneth W. Kinzler0
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Patent abstract
A human gene has been discovered which is genetically altered in human tumor cells. The genetic alteration is gene amplification and leads to a corresponding increase in gene products. Detecting that the gene, designated hMDM2, has become amplified or detecting increased expression of gene products is diagnostic of tumorigenesis. Human MDM2 protein binds to human p53 and allows the cell to escape from p53-regulated growth.
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US Patent 07402570 Amplification of human MDM2 gene in human tumors US Patent 7402570 Amplification of human MDM2 gene in human tumors
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Patent Number
07402570
Patent Number
7402570
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US Patent 07402570 Amplification of human MDM2 gene in human tumors
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Is a
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Patent jurisdiction
Patent number
07402570
Date of patent
July 22, 2008
Patent application number
09966724
Date Filed
October 1, 2001
Patent primary examiner
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