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US Patent 7351869 Crystallization method for purification of calcipotriene

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Patent
Patent
1

Patent attributes

Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
1
Patent Number
73518691
Patent Inventor Names
Anchel Schwartz1
Asher Maimon1
Date of Patent
April 1, 2008
1
Patent Application Number
107171481
Date Filed
November 18, 2003
1
Patent Primary Examiner
‌
Shelley A. Dodson
1
Patent abstract

Provided is a crystallization method for reducing the level of impurities in calcipotriene in which a solution of a starting calcipotriene in a first process solvent, for example THF, is combined with second process solvent, for example methyl formate, and, after cooling, calcipotriene is isolated. The method can include a slurry step for reducing the level of residual first process solvent.

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