Patent 7348184 was granted and assigned to Bio-Rad Laboratories on March, 2008 by the United States Patent and Trademark Office.
This invention provides methods and materials for mapping interaction characteristics between components of a multicomponent biological complex. The methods involve capturing a multicomponent complex on a solid support and washing the support with a series of elution washes forming a gradient of solute concentrations, and determining whether a particular elution wash eluted a particular component.