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US Patent 7056713 Urate oxidase

Patent 7056713 was granted and assigned to Duke University on June, 2006 by the United States Patent and Trademark Office.

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Patent attributes

Current Assignee

Duke University

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Michael Hershfield1

Susan J. Kelly1

Date of Patent

June 6, 2006

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Patent Application Number

097620971

Date Filed

August 5, 1999

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Patent Citations Received

US Patent 11982670 Methods and kits for predicting infusion reaction risk and antibody-mediated loss of response by monitoring serum uric acid during pegylated uricase therapy

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US Patent 12121566 Methods for treating gout

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Patent Primary Examiner

Charles L. Patterson, Jr.

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Patent abstract

The present invention relates, in general, to urate oxidase (uricase) proteins and nucleic acid molecules encoding same. In particular, the invention relates to uricase proteins which are particularly useful as, for example, intermediates for making improved modified uricase proteins with reduced immunogenicity and increased bioavailability.

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