A wrist brace comprising in combination, a flexible holder to receive the user's wrist and having two flaps adapted to be closed toward one another or toward the wrist to secure the holder about the wrist of the user, a carrier flap on the holder, tightening straps associated with the carrier flap, at the straps having end portions anchored by the carrier, loops on a flap to pass the straps, the straps and carrier having connective material thereon, whereby the straps can be pulled and tightened after passing through said loops, to adjustably press-together on the connective material on the carrier.