US Patent 6924267 Methods and active substances for protecting organs
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Patent abstract
The present invention comprises a method of protecting organs or tissue susceptible to reperfusion-induced dysfunction after ischemia. The method comprises parenterally administering to a patient a therapeutical composition containing natural alpha-1 acid glycoprotein, natural alpha-1 antitrypsin or a mixture thereof. Alternatively, organ or tissue transplants can be contacted with natural alpha-1 acid glycoprotein, natural alpha-antitrypsin or mixtures by perfusing or flushing them with a solution containing natural alpha-1 acid glycoprotein, natural alpha-1 antitrypsin or mixtures thereof in a concentration of 0.1 to 5 g/l.
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Patent Inventor Names
Cornelis van't Veer0
Geertrui Denecker0
Jaakko Parkkinen0
Marc A. R. C. Daemen0
Peter Vandenabeele0
Tim G. A. M. Wolfs0
Vincent H. Heemskerk0
Wim A. Buurman0
Date of Patent
August 2, 2005
0Patent Application Number
099566060
Date Filed
September 18, 2001
0Patent Primary Examiner
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US Patent 6924267 Methods and active substances for protecting organs
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