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US Patent 11952427 Anti-CD40 antibodies and uses thereof

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Patent abstractTimelineTable: Further ResourcesReferences
Is a
Patent
Patent
1

Patent attributes

Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
1
Patent Number
119524271
Patent Inventor Names
Bryan C. Barnhart1
Shannon L. Okada1
Brigitte Devaux1
Brenda L. Stevens1
James William West1
Aaron P. Yamniuk1
Date of Patent
April 9, 2024
1
Patent Application Number
176948901
Date Filed
March 15, 2022
1
Patent Citations
‌
US Patent 7867491 Immunoglobulin fusion proteins
1
‌
US Patent 7943743 Human monoclonal antibodies to programmed death ligand 1 (PD-L1)
1
‌
US Patent 8217149 Anti-PD-L1 antibodies, compositions and articles of manufacture
1
‌
US Patent 8367805 Fc variants with altered binding to FcRn
1
‌
US Patent 8629113 CTLA4-Ig immunoadhesins
1
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US Patent 8518404 Activatable binding polypeptides and methods of identification and use thereof
1
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US Patent 11306149 Anti-CD40 antibodies and uses thereof
1
‌
US Patent 7338660 Methods of treating cancer and enhancing immune responses with antibodies that bind CD40
1
...
Patent Primary Examiner
‌
Amy E Juedes
1
CPC Code
‌
C12N 15/63
1
‌
C07K 16/2878
1
Patent abstract

Provided herein are agonistic antibodies, or antigen binding portions thereof, that bind to human CD40 and comprise improved heavy and light chain variable regions that impart improved yield and reduced aggregation. The invention also provides methods of treatment of cancer or chronic infection by administering the antibodies of the invention to a subject in need thereof.

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