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Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Bryan C. Barnhart1
Shannon L. Okada1
Brigitte Devaux1
Brenda L. Stevens1
James William West1
Aaron P. Yamniuk1
Date of Patent
April 9, 2024
1Patent Application Number
176948901
Date Filed
March 15, 2022
1Patent Citations
...
Patent Primary Examiner
CPC Code
Patent abstract
Provided herein are agonistic antibodies, or antigen binding portions thereof, that bind to human CD40 and comprise improved heavy and light chain variable regions that impart improved yield and reduced aggregation. The invention also provides methods of treatment of cancer or chronic infection by administering the antibodies of the invention to a subject in need thereof.
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