An information handling system mouse includes a motion power switch that applies power to the mouse when the mouse is moved in a powered down state to restart the mouse processing resource and position sensor. When a mouse is inactive for predetermined conditions, such as an idle time, the processing resource enables the motion power switch and cuts off power to the mouse. The motion power switch consumes no power until motion of the mouse closes a circuit that reactivates the processing resource to manage the mouse power state. The result is a mouse idle state with no power use and a rapid wake to an operational state.