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US Patent 11763915 Methods for detecting nucleic acid variants

Patent 11763915 was granted and assigned to Ultima Genomics, Inc. on September, 2023 by the United States Patent and Trademark Office.

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Patent abstractTimelineTable: Further ResourcesReferences
Is a
Patent
Patent

Patent attributes

Patent Applicant
Ultima Genomics, Inc.
Ultima Genomics, Inc.
Current Assignee
Ultima Genomics, Inc.
Ultima Genomics, Inc.
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
11763915
Patent Inventor Names
Simchon Faigler
Mark Pratt
Yoav Etzioni
Florian Oberstrass
Gilad Almogy
Date of Patent
September 19, 2023
Patent Application Number
16864981
Date Filed
May 1, 2020
Patent Citations
‌
US Patent 11220709 RNA sequencing methods
‌
US Patent 8772473 Mostly natural DNA sequencing by synthesis
‌
US Patent 9416413 Alternative nucleotide flows in sequencing-by-synthesis methods
‌
US Patent 9817944 Systems and methods for analyzing sequence data
‌
US Patent 10344328 Methods for biological sample processing and analysis
‌
US Patent 11220710 RNA sequencing methods
Patent Primary Examiner
‌
G Steven Vanni
Patent abstract

Methods for detecting a short genetic variant in a test sample are described herein. In some exemplary methods, the short genetic variant is called using one or more match scores, which are determined using one or more sequencing data sets obtained from a test nucleic acid molecule, wherein the test sequencing data sets are determined by sequencing the test nucleic acid molecule using non-terminating nucleotides provided in separate nucleotide flows according to a flow-cycle order. Also described herein are methods of sequencing a test nucleic acid molecule using two or more different flow-cycle orders and/or extended flow cycle orders having five or more nucleotide flows per flow cycle.

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