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US Patent 11555061 Albumin variants and conjugates

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Is a
Patent
Patent

Patent attributes

Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
11555061
Date of Patent
January 17, 2023
Patent Application Number
16827356
Date Filed
March 23, 2020
Patent Citations
‌
US Patent 10329340 Albumin variants
‌
US Patent 10501524 Albumin variants
‌
US Patent 10633428 Albumin variants and conjugates
‌
US Patent 10711050 Variant serum albumin with improved half-life and other properties
‌
US Patent 10696732 Albumin variants
‌
US Patent 10934341 Albumin variants
‌
US Patent 10208102 Albumin variants and uses thereof
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US Patent 10233228 Albumin derivatives and variants
Patent Citations Received
‌
US Patent 12116400 Albumin variants and conjugates
8
Patent Primary Examiner
‌
Suzanne M Noakes

Based on the three-dimensional structure of albumin, the inventors have designed variant polypeptides (muteins) which have one or more cysteine residues with a free thiol group (hereinafter referred to as “thio-albumin”). The variant polypeptide may be conjugated through the sulphur atom of the cysteine residue to a conjugation partner such as a bioactive compound.

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