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US Patent 10947579 Recovering long-range linkage information from preserved samples

Patent 10947579 was granted and assigned to Dovetail Genomics, Llc on March, 2021 by the United States Patent and Trademark Office.

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Patent abstractTimelineTable: Further ResourcesReferences
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Patent
Patent

Patent attributes

Patent Applicant
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Dovetail Genomics, Llc
Current Assignee
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Dovetail Genomics, Llc
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
10947579
Patent Inventor Names
Nicholas H. Putnam2
Paul Hartley2
Christopher John Troll2
Marco Blanchette2
Martin P. Powers2
Date of Patent
March 16, 2021
Patent Application Number
16053610
Date Filed
August 2, 2018
Patent Citations Received
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US Patent 12065691 Recovering long-range linkage information from preserved samples
1
Patent Primary Examiner
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Ethan C. Whisenant
Patent abstract

The disclosure provides methods to isolate genome or chromosome level structural information from preserved samples. In some cases, samples preserved under conditions where long-range nucleic acid information is believed to be irreparably lost, such as FFPE samples, are treated to recover nucleic acid-protein complexes stabilized as part of the sample preservation process. The complexes are processed so as to recover information regarding which nucleic acids are bound to a common complex, and the information is used to recover genomic structural information.

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