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US Patent 10336818 Fc variants with altered binding to FcRn

Patent 10336818 was granted and assigned to Xencor on July, 2019 by the United States Patent and Trademark Office.

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Patent abstractTimelineTable: Further ResourcesReferences
Is a
Patent
Patent

Patent attributes

Patent Applicant
Xencor
Xencor
Current Assignee
Xencor
Xencor
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
10336818
Date of Patent
July 2, 2019
Patent Application Number
14459160
Date Filed
August 13, 2014
Patent Citations Received
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US Patent 12110324 Antigen binding molecules targeting thymic stromal lymphopoietin (TSLP)
3
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US Patent 11993644 Antigen binding molecules targeting SARS-CoV-2
4
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5
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US Patent 12103954 Heterodimeric Fc cytokines and uses thereof
6
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US Patent 10836825 Multispecific antibodies that target HIV GP120 and CD3
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US Patent 10882898 Human immunodeficiency virus neutralizing antibodies
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US Patent 10882907 Multispecific antibodies that target HIV GP120 and CD3
‌
US Patent 11597759 Multispecific antibodies that target HIV GP120 and CD3
...
Patent Primary Examiner
‌
Chun W Dahle
Patent abstract

The present application relates to a variant Fc region comprising at least one modification relative to a wild-type human Fc region, where the modification selected from the group consisting of 434S, 252Y/428L, 252Y/434S, and 428L/434S, and the numbering is according to the EU index.

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