Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Pak Poon0
Carla Zimmerman0
Chris McMaster0
Michel Roberge0
Date of Patent
May 28, 2019
0Patent Application Number
153029300
Date Filed
April 10, 2015
0Patent Primary Examiner
Patent abstract
Methods are provided for the treatment of Parkinson's disease (PD) in patients bearing mutations in the LRRK2 gene. A therapeutically effective amount of piperazine derivative compounds are employed to inhibit the biological activity of ArfGAP1, inhibition that counteracts the deleterious effects of mutations in, or increased expression of, the LRRK2 protein.
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