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US Patent 10016435 Use of inhibitors of Bruton's tyrosine kinase (Btk)

Patent 10016435 was granted and assigned to Pharmacyclics on July, 2018 by the United States Patent and Trademark Office.

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Contents

Is a
Patent
Patent

Patent attributes

Patent Applicant
Pharmacyclics
Pharmacyclics
Current Assignee
Pharmacyclics
Pharmacyclics
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
10016435
Patent Inventor Names
Laurence Elias0
Eric Hedrick0
Gwen Fyfe0
Joseph J. Buggy0
Tarak D. Mody0
David J. Loury0
Date of Patent
July 10, 2018
Patent Application Number
15715995
Date Filed
September 26, 2017
Patent Citations Received
‌
US Patent 11433072 Oral dosage forms of ibrutinib
0
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US Patent 10653696 Use of inhibitors of bruton's tyrosine kinase (BTK)
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US Patent 10751342 Use of inhibitors of Bruton's tyrosine kinase (Btk)
0
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US Patent 10752594 JAK1 and ALK2 inhibitors and methods for their use
0
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US Patent 10888562 AXL kinase inhibitors and use of the same
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US Patent 10954567 Mutations associated with resistance to inhibitors of Bruton's Tyrosine Kinase (BTK)
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US Patent 11013741 AXL kinase inhibitors and use of the same
‌
US Patent 11040038 Methods for treating diseases associated with abnormal ACVR1 expression and ACVR1 inhibitors for use in the same
...
Patent Primary Examiner
‌
Umamaheswari Ramachandran
Patent abstract

Disclosed herein are methods for treating a cancer comprising: a. administering a Btk inhibitor to a subject sufficient to result in an increase or appearance in the blood of a subpopulation of lymphocytes defined by immunophenotyping; b. determining the expression profile of one or more biomarkers from one or more subpopulation of lymphocytes; and c. administering a second agent based on the determined expression profile.

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