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Potassium, Hydration, Cardiovascular, and Kidney Study

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clinicaltrials.gov/study/NCT06062017
Is a
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Clinical study
0

Clinical Study attributes

NCT Number
NCT060620170
Health Conditions in Trial
‌
Hydration
0
Blood pressure
Blood pressure
0
Trial Recruitment Size
400
Trial Sponsor
Auburn University
Auburn University
0
Trial Collaborator
Indiana University
Indiana University
0
Clinical Trial Start Date
2023
0
Primary Completion Date
2025
0
Study Completion Date
2026
0
Clinical Trial Study Type
Interventional0
Interventional Trial Purpose
Prevention0
Intervention Type
Dietary Supplement0
Other0
Intervention Name
Water and Potassium supplementation0
Water alone0
Interventional Trial Phase
Not Applicable0
Official Name
The Effects of Water and Potassium Supplementation on Cardiovascular and Kidney Function in Young Black Adults0
Last Updated
October 3, 2023
0
Allocation Type
Randomized0
Intervention Model
Parallel Assignment0
Masking Type
Triple0
Masked Party
Participant0
Outcomes Assessor0
Investigator0
Study summary

Compared with White Adults, Non-Hispanic Black Adults are at an elevated risk of developing cardiovascular disease (CVD) and end stage chronic-kidney disease (CKD), two of the leading causes of death in the United States. Inadequate hydration status is associated with risk factors for both CVD and CKD. Prior data show that Black individuals are less likely to be adequately hydrated when compared with their White counterparts. Further, socioeconomic factors have been shown to influence hydration practices. Inadequate hydration influences certain hormones that regulate blood volume and impact blood pressure, but increasing potassium intake may provide some positive effects on normalizing these hormones and blood pressure. Black adults, in particular, are more likely to consume less potassium, have inadequate hydration, and tend to have higher blood pressure. As such, there is a critical need for effective strategies to address racial disparities in hydration and resultant health consequences; as well as establish the role of socioeconomic factors contributing to hydration. Therefore, the investigators are seeking to test the investigators' central hypothesis that both water, and to a greater extent, water with a potassium supplement will improve hydration and cardiovascular health in young Black adults (n = 40, 20 females, 20 males). The investigators will assess measures of blood pressure, arterial stiffness, and biomarkers in the urine and blood samples prior to and following a 14-day hydration intervention of either a) bottled water or b) bottled water with potassium supplementation (2000mg potassium/day).

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