Heat Biologics is a company that has developed a T-cell Activation Platform therapy designed to identify oncology and infectious diseases. The company was founded in 2008 by Jeff Wolf, in Chapel Hill, North Carolina, United States.
Heat Biologics' T-cell Activation Platform can be administered with checkpoint inhibitors and other immuno-modulators.
With the outbreak of COVID-19 (coronavirus), the company has launched a program to develop a vaccine designed to protect against the virus. The company has created a platform called gp96 which has provided treatment and prevention options for the response or induction of mucosal immunity in SIV/HIV, malaria, zika, and other dangerous diseases. Heat Biologics has launched a program with its subsidiary, Zovolax, to use this gpp96 platform to create a vaccine against the SARS-CoV-2 which ultimately causes COVID-19.
The protein gp96 is found in all human cells and takes the responsibility of acting as a "molecular warning system" to induce immunity against necrotic cells. The company believes that this protein is a useful vaccine platform that has been proven to induce immune response and immunity in the case of several infectious disease models. They are working to make this protein platform a viable option against COVID-19 and any variant strand of the virus.
Heat Biologics | Crunchbase
Heat Biologics Launches Program to Develop Vaccine Designed to Protect Against COVID-19 Coronavirus
March 3, 2020
Heat Biologics, Inc.
March 5, 2020
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Chapel Hill, North Carolina, United States
- CompanyA company, abbreviated 'co.', is a legal entity made up of an association of people, be they natural, legal, or a mixture of both, for carrying on a commercial or industrial enterprise.
- ImmunotherapyImmunotherapy aims to treat disease through activation or suppression of an immune response. For example activating immunotherapies can target cancer and suppressive immunotherapies can target autoimmunity.
- VaccinationAdministration of antigenic material to stimulate an individual's immune system to develop adaptive immunity to a pathogen
- Cluster: COVID-19A cluster of topics related to COVID-19. COVID-19 is the abbreviated name for coronavirus disease 2019, a respiratory disease caused by a novel coronavirus strain called SARS-CoV-2. COVID-19 was first detected in Wuhan City, China and the outbreak was declared a pandemic on March 11, 2020 by the WHO.
- CoronavirusCDC Coronavirus: Coronaviruses are common throughout the world. They can infect people and animals. Five different coronaviruses can infect people and make them sick. They usually cause mild to moderate upper-respiratory illness.